Author: LG

Invited speaker: Natalia Soshnikova

We have the pleasure of hosting Dr. Natalia Soshnikova from the Institute of Molecular Biology gGmbH (IMB) in Mainz, Germany. She will talk about the molecular mechanisms of intestinal stem cell specification during development.

More details about her research here: Soshnikova Lab

Date: Thursday 18th of January
Time: 10:30 – 11:10 + discussions
Place: BUS1: Meeting-room Pankreas (6th floor, KGJ for Diabetes)

Microsoft Word - SEMINAR-Natalia.docx
Some Selected Papers produced by the Soshnikova lab:

  • Dzama MM, Nigmatullina L, Sayols S, Kreim N and Soshnikova N (2017). Distinct populations of embryonic epithelial progenitors generate Lgr5+ intestinal stem cells. Dev Biol, pii: S0012-1606(17)30576-6. doi: 10.1016/j.ydbio.2017.10.012
  • Kazakevych J, Sayols S, Messner B, Krienke C and Soshnikova N (2017). Dynamic changes in chromatin states accompany specification of the adult intestinal stem cells. Nucleic Acids Res, 45(10):5770-5784. doi: 10.1093/nar/gkx167
  • Nigmatullina L, Norkin M, Dzama MM, Messner B, Sayols S, Soshnikova N (2017). Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development. EMBO J, 36: 869-885. doi: 10.15252/embj.201694959 (recommended by F1000Prime)
  • Jung H, Mazzoni EO, Soshnikova N, Hanley O, Venkatesh B, Duboule D, Dasen JS (2014). Evolving Hox activity profiles govern diversity in locomotor systems. Dev Cell, 29, 171-187
  • Schorderet P, Lonfat N, Darbellay F, Tschopp P, Gitto S, Soshnikova N, Duboule D (2013). A genetic approach to the recruitment of PRC2 at the HoxD locus. PLoS Genet, 9, e1003951
  • Montavon T, Soshnikova N, Mascrez B, Joye E, Thevenet L, Splinter E, de Laat W, Spitz F and Duboule D (2011). A regulatory archipelago controls Hox genes transcription in digits. Cell, 147, 1132-1145
  • Soshnikova N, Montavon T, Leleu M, Galjart N and Duboule D (2010). Functional analysis of CTCF during mammalian limb development. Dev Cell, 19, 819-830
  • Soshnikova N and Duboule D (2009). Epigenetic temporal control of mouse Hox genes in vivo. Science, 324, 1320-1323

Please share with your colleagues and students, and show your support by attending the seminar.




BSCC Christmas seminar: Anne Mette Søviknes

We would like to invite you to the BSCC Christmas seminar on Friday, December 15th, 12:00 o’clock at Birkhaugsalen. For details, please see the attached poster. 

Please share with your colleagues and students, and show your support by attending the seminar.


2017-12-15 BSCC Christmas seminar 2017

Stamcelleforskning – i dag og i morgen

Program for stamcelleforskning (2013–2017) har hatt som mål å utvikle og styrke kompetansen innenfor grunnleggende og klinisk forskning på stamceller, med sikte på behandling av alvorlig og kronisk syke pasienter.

Programmet har hatt tre hovedpilarer: Støtte til prosjekter basert på åpen konkurransebasert utlysning av forsknings- midler, bevilgning til Nasjonalt senter for stamcelleforskning, og finansiering av det årlige nettverksmøtet for norsk stamcelleforskning. Programstyret har gjennom disse virkemidlene bygget opp norsk stamcelleforskning.

Programmet har hatt fire prioriterte tematiske områder:
• Forskning for bedre forståelse av basale prosesser knyttet til vekst og differensiering av stamceller.
• Karakterisering og validering av stamceller for bruk i klinikken.
• Utvikling og implementering av prosedyrer og protokoller for reparasjon av skadet vev eller organ.
• Bruk og videreutvikling av induserte pluripotente stamceller (iPS-celler).

Mer informasjon på programmets hjemmeside.

Formidlingsbrosjyre Program for stamcelleforskning



Laurence Hoareau and Manuel Carrasco joined the lab

We are welcoming two new postdoctoral fellows to our research group.

Laurence Hoareau is a scientist in cell biology, molecular biology and biochemistry. She has been working for 10 years in the field of adipose tissue inflammation linked to obesity-associated diseases. Her work is essentially based on human primary culture of adipose tissue, adipocytes and stromal cells, which lead to around 20 publications. Laurence is from Reunion Island (French overseas department in Indian Ocean). She obtained her Bachelor’s degree from University of Reunion Island, her Master degree from University Pierre & Marie Curie (Paris, France) and her Ph.D in Biochemistry, Molecular and Cellular Biology from University of Reunion Island.

Manuel Carrasco recently obtained his PhD from the Andalusian Molecular Biology and Regenerative Medicine Centre in Seville, Spain. Manuel’s research was focused on how transcriptional networks control pancreas and liver development and function by using mouse models (conditional knockout mice, reporter transgenic lines, cell culture, etc.). More specifically, Manuel studied the contribution of GATA transcription factors to pancreas organogenesis, regeneration and function. Manuel obtained his Bachelor degree from University of Seville and his Master degree from University Pablo de Olavide (Sevilla, Spain).


Laurence Hoareau and Manuel Carrasco enjoying our first “get-together” dinner

Our confocal is in place!

After more than 6 months of waiting, planing, arguing, more planing, we have our own old but still functional SP2 Leica confocal set in place. Of course, we lost some screws during its movement, but thanks to the great administrative skills of Helge, we have now all that is needed.  So, I have many thanks for:

  • Helge and Simona, which convinced the MIC platform not to retire this great machine (my favourite), and we promise that we’ll still use the MIC confocals (ofc, they have SP5 and SP8!);
  • MIC people, especially Hege and Endy, which took really good care of this machine that is now in our care;
  • Bård-Arne Pedersen from Ortomedic, which managed to put all the pieces back together in ONE day! 


Norwegian Press Reviews

We are very grateful and happy to announce that our research article was discussed in several interviews, where Helge explained the current status of diabetes research and our contribution. You can find the the press articles (in Norwegian) below:

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interview for nrk

interview for

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